Arthritis: Arthritis is a broad term referring to joint inflammation, which manifests in diverse forms, impacting individuals of all ages, genders, and backgrounds. This section provides a general overview of arthritis, its prevalence, and the impact it has on overall health. Rheumatoid Arthritis: Rheumatoid arthritis (RA) is an autoimmune disorder characterized by chronic inflammation primarily affecting the joints. Here, we explore the intricacies of RA, including its pathophysiology, risk factors, and the importance of early diagnosis and intervention in managing this condition effectively. Autoimmune Mechanisms: Immune System Dysfunction : In RA, the body's immune system mistakenly attacks its own tissues, particularly the synovium, triggering inflammation. Autoantibodies : One of the hallmarks of RA is the presence of autoantibodies, such as rheumatoid factor (RF) and anti-citrullinated protein antibodies (ACPAs), which contribute to joint inflammation and damage. Cytokine Imb...
- Get link
- X
- Other Apps